Description

2-Hydrazino-4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating a pyrimidine core, a thiophene ring, and a trifluoromethyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, leveraging the biological activity of the pyrimidine-thiophene scaffold.
• Chemical Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic systems in organic and medicinal chemistry.
• Material Science Research: Investigated for potential use in creating organic electronic materials due to its conjugated structure.
• Biochemical Tool Compound: Utilized in life science research as a probe or inhibitor to study specific enzymatic pathways.

Basic Information

Product Name	2-Hydrazino-4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidine
CAS No.	861432-48-6
Molecular Formula	C10H8F3N4S
Molecular Weight	273.26 g/mol
Synonyms	2-Hydrazinyl-4-(5-methylthiophen-2-yl)-6-(trifluoromethyl)pyrimidine; 4-(5-Methyl-2-thienyl)-6-(trifluoromethyl)-2-pyrimidinylhydrazine; 2-Hydrazino-4-(5-methyl-2-thienyl)-6-(trifluoromethyl)pyrimidine; 861432-48-6; 6-(Trifluoromethyl)-4-(5-methylthien-2-yl)pyrimidin-2-ylhydrazine
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-4-(5-Methylthien-2-Yl)-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.