Description

4-Chloro-2-(2-Chloro-Pyridin-4-Yl)-Quinazoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazoline-pyridine scaffold, featuring reactive chlorine substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D and agrochemical research teams for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents for oncology and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its bioactive heterocyclic core.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor modulators for biological studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	4-Chloro-2-(2-Chloro-Pyridin-4-Yl)-Quinazoline
CAS No.	861418-44-2
Molecular Formula	C₁₃H₇Cl₂N₃
Molecular Weight	276.12 g/mol
Synonyms	4-Chloro-2-(2-chloropyridin-4-yl)quinazoline; 2-(2-Chloro-4-pyridinyl)-4-chloroquinazoline; Quinazoline, 4-chloro-2-(2-chloro-4-pyridinyl)-; 4-Chloro-2-(2-chloro-4-pyridyl)quinazoline; 861418-44-2; 4-Chloro-2-(2-chloro-pyridin-4-yl)-quinazoline
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(2-Chloro-Pyridin-4-Yl)-Quinazoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.