Description

5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its unique pyrazolopyrimidine core.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and tool compounds for target identification and validation.
• Material Science: Investigated as a building block for advanced organic electronic materials and functional polymers.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production for high-throughput screening.

Basic Information

Product Name	5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	861408-98-2
Molecular Formula	C11H8F3N3O2
Molecular Weight	271.20 g/mol
Synonyms	5-Cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 7-(Trifluoromethyl)-5-cyclopropylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 861408-98-2; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-cyclopropyl-7-(trifluoromethyl)-; 5-Cyclopropyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to support regulatory filings and ensure batch-to-batch consistency for critical R&D and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.