Description

7-(4-Methoxyphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, synthetically derived heterocyclic carboxylic acid building block. This compound is of significant commercial interest as a key intermediate in the research and development of novel pharmaceutical agents, particularly in kinase inhibitor and anti-cancer drug discovery programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	7-(4-Methoxyphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	861407-96-7
Molecular Formula	C14H11N3O3
Molecular Weight	269.26 g/mol
Synonyms	7-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 7-(p-Methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 7-(4-Methoxyphenyl)-3-pyrazolo[1,5-a]pyrimidinecarboxylic acid; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(4-methoxyphenyl)-; 861407-96-7; 7-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (deprotonated form)
EINECS	Contact for details

Quality Control

Our production of 7-(4-Methoxyphenyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality systems are designed to support cGMP compliance for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.