Description

[4-Difluoromethyl-6-(3-Methoxyphenyl)-Pyrimidin-2-Yl]-Hydrazine is a high-purity, specialized pyrimidine derivative used as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluoromethyl and hydrazine functionalities enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific structural motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the pyrimidine core for biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial labs.
• Material Science: Potential intermediate for creating specialized polymers or organic electronic materials with tailored properties.

Basic Information

Product Name	[4-Difluoromethyl-6-(3-Methoxyphenyl)-Pyrimidin-2-Yl]-Hydrazine
CAS No.	861226-63-3
Molecular Formula	C12H12F2N4O
Molecular Weight	266.25 g/mol
Synonyms	4-(Difluoromethyl)-6-(3-methoxyphenyl)-2-pyrimidinylhydrazine; 6-(3-Methoxyphenyl)-4-(difluoromethyl)-2-pyrimidinylhydrazine; (4-Difluoromethyl-6-(3-methoxyphenyl)pyrimidin-2-yl)hydrazine; 2-Hydrazinyl-4-(difluoromethyl)-6-(3-methoxyphenyl)pyrimidine; 861226-63-3; [4-(Difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]hydrazine
EINECS	Contact for details

Quality Control

Our [4-Difluoromethyl-6-(3-Methoxyphenyl)-Pyrimidin-2-Yl]-Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.