Description

4-(Difluoromethyl)-6-(3,4-Dimethylphenyl)-2-Hydrazinopyrimidine is a specialized pyrimidine derivative, a high-value chemical intermediate designed for advanced synthesis. Its core value lies in its unique difluoromethyl and hydrazine functional groups, which are critical for introducing specific physicochemical properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the pyrimidine core.
• Chemical Research & Development: Serves as a versatile precursor for creating complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Potential intermediate in the synthesis of specialty chemicals and advanced materials, such as ligands for catalysts or organic electronic components.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination and nitrogen-containing heterocycles.

Basic Information

Product Name	4-(Difluoromethyl)-6-(3,4-Dimethylphenyl)-2-Hydrazinopyrimidine
CAS No.	861225-97-0
Molecular Formula	C13H14F2N4
Molecular Weight	264.27 g/mol
Synonyms	2-Hydrazinyl-4-(difluoromethyl)-6-(3,4-dimethylphenyl)pyrimidine; 4-(Difluoromethyl)-6-(3,4-dimethylphenyl)-2-pyrimidinamine, N-amino-; 6-(3,4-Dimethylphenyl)-4-(difluoromethyl)-2-hydrazinylpyrimidine; 4-(Difluoromethyl)-6-(3,4-dimethylphenyl)pyrimidin-2-ylhydrazine; 2-Hydrazino-4-(difluoromethyl)-6-(3,4-dimethylphenyl)pyrimidine; CAS 861225-97-0
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethyl)-6-(3,4-Dimethylphenyl)-2-Hydrazinopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Assay (Titration)	≥ 96.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.