Description

(E)-2-(2-Fluorophenyl)-3-[3-(2-Pyrimidinyloxy)Phenyl]-2-Propenenitrile is a specialized organic intermediate featuring a unique molecular scaffold combining fluorophenyl, propenenitrile, and pyrimidinyloxy phenyl groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical candidates and agrochemicals, enabling the development of novel bioactive molecules. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Serves as a core structure for developing new-generation herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in academic and industrial research to study protein-ligand interactions and biological mechanisms due to its distinctive heterocyclic architecture.
• Material Science Precursor: Potential building block for creating functional organic materials, such as liquid crystals or organic semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	(E)-2-(2-Fluorophenyl)-3-[3-(2-Pyrimidinyloxy)Phenyl]-2-Propenenitrile
CAS No.	861210-17-5
Molecular Formula	C19H12FN3O
Molecular Weight	317.32 g/mol
Synonyms	(E)-2-(2-Fluorophenyl)-3-[3-(pyrimidin-2-yloxy)phenyl]prop-2-enenitrile; 2-Propenenitrile, 2-(2-fluorophenyl)-3-[3-(2-pyrimidinyloxy)phenyl]-, (2E)-; 861210-17-5; (E)-3-(3-((Pyrimidin-2-yl)oxy)phenyl)-2-(2-fluorophenyl)acrylonitrile; 2-(2-Fluorophenyl)-3-[3-(pyrimidin-2-yloxy)phenyl]acrylonitrile (E)-isomer
EINECS	Contact for details

Quality Control

Our (E)-2-(2-Fluorophenyl)-3-[3-(2-Pyrimidinyloxy)Phenyl]-2-Propenenitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.