Description

5-Bromo-3-Methyl-3,4-Dihydroquinazolin-2(1H)-One is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive chemical space.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or plant growth regulators.
• Organic Synthesis Building Block: Utilized in various organic transformations, including cross-coupling reactions, to introduce the bromoquinazolinone moiety into more complex molecules.
• Chemical Biology Probe Synthesis: Acts as a starting material for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: Potential intermediate for the development of organic electronic materials or advanced polymers with specific functionalities.

Basic Information

Product Name	5-Bromo-3-Methyl-3,4-Dihydroquinazolin-2(1H)-One
CAS No.	861106-66-3
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	5-Bromo-3-methyl-1,2,3,4-tetrahydroquinazolin-2-one; 5-Bromo-3-methyl-3,4-dihydro-2(1H)-quinazolinone; 2(1H)-Quinazolinone, 5-bromo-3,4-dihydro-3-methyl-; 5-Bromo-3-methyl-1,2,3,4-tetrahydroquinazolin-2-one; 5-Bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one; 861106-66-3; 3-Methyl-5-bromo-3,4-dihydroquinazolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-3,4-Dihydroquinazolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your research and development needs with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.