Description

6-Oxo-1,6-Dihydropyrimidine-2-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for its versatile reactivity and role in creating novel nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require specific pyrimidine-based scaffolds for bioactivity.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating complex, high-value specialty chemicals and ligands for catalysis.
• Academic & R&D: Serves as a valuable starting material in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its carboxylic acid and heterocyclic functionalities.

Basic Information

Product Name	6-Oxo-1,6-Dihydropyrimidine-2-Carboxylic Acid
CAS No.	861033-60-5
Molecular Formula	C5H4N2O3
Molecular Weight	140.10 g/mol
Synonyms	2-Pyrimidinecarboxylic acid, 1,6-dihydro-6-oxo-; 1,6-Dihydro-6-oxo-2-pyrimidinecarboxylic acid; 6-Hydroxy-2-pyrimidinecarboxylic acid; 2-Carboxy-6-hydroxypyrimidine; 6-Hydroxypyrimidine-2-carboxylic acid; Dihydrouracil-2-carboxylic acid; Uracil-2-carboxylic acid (tautomer)
EINECS	Contact for details

Quality Control

Our 6-Oxo-1,6-Dihydropyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.