Description

4-Chloro-5-Fluoropyridine-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is prized for its unique halogenated pyridine core, which facilitates the development of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.
• Academic & Industrial R&D: A versatile reagent for exploratory chemistry in both academic laboratories and industrial R&D departments.

Basic Information

Product Name	4-Chloro-5-Fluoropyridine-3-Carboxylic Acid
CAS No.	860296-20-4
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	3-Pyridinecarboxylic acid, 4-chloro-5-fluoro-; 4-Chloro-5-fluoronicotinic acid; 5-Fluoro-4-chloropyridine-3-carboxylic acid; 4-Chloro-5-fluoro-3-pyridinecarboxylic acid; 860296-20-4; 4-Chloro-5-fluoropyridine-3-carboxylate; 4-Chloro-5-fluoronicotinate
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Fluoropyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.