Description

n-Methyl-n-(4-Pyrimidin-5-Ylbenzyl)Amine is a high-purity, advanced pharmaceutical intermediate with the CAS number 859850-85-4. This compound is a critical building block in modern medicinal chemistry, valued for its unique pyrimidine-benzylamine scaffold which is integral to the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for targeted therapies.
• Kinase Inhibitor Development: Serves as a core structural component in the research and production of protein kinase inhibitors for cancer treatment.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory drug discovery programs.

Basic Information

Product Name	n-Methyl-n-(4-Pyrimidin-5-Ylbenzyl)Amine
CAS No.	859850-85-4
Molecular Formula	C13H13N3
Molecular Weight	211.26 g/mol
Synonyms	N-Methyl-1-(4-(pyrimidin-5-yl)phenyl)methanamine; 5-((Methylamino)methyl)-N-methylpyrimidin-2-amine; 1-(4-Pyrimidin-5-ylphenyl)-N-methylmethanamine; N-Methyl-4-(pyrimidin-5-yl)benzylamine; 859850-85-4; 4-(Pyrimidin-5-yl)-N-methylbenzylamine
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(4-Pyrimidin-5-Ylbenzyl)Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.