Description

7-Benzyl-4-Chloro-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including potential treatments for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of targeted kinase inhibitor drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under GMP conditions.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying specific biological pathways and enzyme functions.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	7-Benzyl-4-Chloro-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine
CAS No.	859826-11-2
Molecular Formula	C16H16ClN3S
Molecular Weight	317.83 g/mol
Synonyms	7-Benzyl-4-chloro-2-(methylthio)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 4-Chloro-2-(methylthio)-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 7-Benzyl-4-chloro-2-methylsulfanyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; Tetrahydropyrido[3,4-d]pyrimidine, 7-benzyl-4-chloro-2-(methylthio)-5,6,7,8-; CAS 859826-11-2
EINECS	Contact for details

Quality Control

Our production of 7-Benzyl-4-Chloro-2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.