Description

Cytosine, n-Acetyl-N,1-Dimethyl- (5Ci) is a modified nucleobase derivative, specifically an N-acetylated and N-methylated analog of cytosine. This compound is of significant value in pharmaceutical research and development as a key building block for novel nucleoside analogs and potential therapeutic agents. It is primarily needed by researchers and manufacturers in the fields of medicinal chemistry, antiviral drug discovery, and the synthesis of modified oligonucleotides for diagnostic applications.

Application

• Medicinal Chemistry Intermediate: Serves as a crucial synthetic precursor for the development of novel nucleoside-based pharmaceuticals.
• Antiviral Drug Research: Used in the synthesis of modified nucleosides being investigated for activity against various viral targets.
• Oligonucleotide Synthesis: Acts as a protected or modified monomer for creating specialized DNA/RNA sequences with altered properties.
• Biochemical Research: Employed in studies exploring enzyme-substrate interactions, particularly with methyltransferases and acetyltransferases.
• Chemical Biology Probes: Utilized to develop labeled or tagged nucleobase analogs for tracking biological processes.
• Reference Standard: Functions as a high-purity analytical standard for quality control in related API manufacturing.

Basic Information

Product Name	Cytosine, n-Acetyl-N,1-Dimethyl- (5Ci)
CAS No.	859739-98-3
Molecular Formula	C8H11N3O2
Molecular Weight	181.19 g/mol
Synonyms	1-Methyl-N-acetylcytosine; N-Acetyl-1-methylcytosine; 4-Acetylamino-1-methyl-2(1H)-pyrimidinone; 4-(Acetylamino)-1-methyl-1H-pyrimidin-2-one; N4-Acetyl-1-methylcytosine; 1-Methyl-N4-acetylcytosine; 2(1H)-Pyrimidinone, 4-(acetylamino)-1-methyl-; Modified Cytosine Derivative
EINECS	Contact for details

Quality Control

Our Cytosine, n-Acetyl-N,1-Dimethyl- (5Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.