Description

Methyl 2-(2-Chloro-5-Nitropyrimidin-4-Ylamino)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-based structure. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily needed by R&D laboratories, process development chemists, and manufacturers within the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially in targeted cancer therapies.
• API Synthesis: Used as a building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) manufacturing processes.
• Biochemical Research: Employed in academic and industrial research for studying enzyme inhibition and developing new therapeutic agents.
• Process Chemistry: Utilized in route scouting and optimization for the development of efficient, scalable commercial production methods.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	Methyl 2-(2-Chloro-5-Nitropyrimidin-4-Ylamino)Acetate
CAS No.	859307-58-7
Molecular Formula	C7H7ClN4O4
Molecular Weight	246.61 g/mol
Synonyms	Methyl N-(2-chloro-5-nitropyrimidin-4-yl)glycinate; 2-Chloro-5-nitro-N-(carboxymethyl)-4-pyrimidinamine methyl ester; Methyl (2-chloro-5-nitropyrimidin-4-ylamino)acetate; Glycine, N-(2-chloro-5-nitropyrimidin-4-yl)-, methyl ester; 859307-58-7; Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)amino)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(2-Chloro-5-Nitropyrimidin-4-Ylamino)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.