Description

6-Amino-5-Chloro-2-Cyclopropylpyrimidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine carboxylic acid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring potent and selective molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral, anticancer, and anti-infective drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides with specific modes of action.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of heterocyclic compounds for screening.
• Academic & R&D: Employed in university and corporate research labs for studying structure-activity relationships (SAR) and reaction mechanisms.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	6-Amino-5-Chloro-2-Cyclopropylpyrimidine-4-Carboxylic Acid
CAS No.	858956-08-8
Molecular Formula	C8H8ClN3O2
Molecular Weight	213.62 g/mol
Synonyms	6-Amino-5-chloro-2-cyclopropyl-4-pyrimidinecarboxylic acid; 2-Cyclopropyl-6-amino-5-chloropyrimidine-4-carboxylic acid; 5-Chloro-6-amino-2-cyclopropylpyrimidine-4-carboxylic acid; ACCPA; 858956-08-8; 6-Amino-5-chloro-2-cyclopropylpyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of 6-Amino-5-Chloro-2-Cyclopropylpyrimidine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles to guarantee reliability for critical pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.