Description

6-Amino-5-Chloro-2-(4-Chloro-Phenyl)-Pyrimidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 858955-38-1. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure and reactivity. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its pyrimidine core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Manufacturing: Employed in the commercial-scale production of specific active pharmaceutical ingredients under GMP conditions.
• Material Science: Investigated for the creation of specialty polymers and organic electronic materials.

Basic Information

Product Name	6-Amino-5-Chloro-2-(4-Chloro-Phenyl)-Pyrimidine-4-Carboxylic Acid
CAS No.	858955-38-1
Molecular Formula	C11H7Cl2N3O2
Molecular Weight	284.10 g/mol
Synonyms	6-Amino-5-chloro-2-(4-chlorophenyl)pyrimidine-4-carboxylic acid; 2-(4-Chlorophenyl)-5-chloro-6-aminopyrimidine-4-carboxylic acid; 858955-38-1; 5-Chloro-6-amino-2-(4-chlorophenyl)-4-pyrimidinecarboxylic acid; 4-Pyrimidinecarboxylic acid, 6-amino-5-chloro-2-(4-chlorophenyl)-; ACCN: OV3855000; UNII: Contact for details
EINECS	Contact for details

Quality Control

Our production of 6-Amino-5-Chloro-2-(4-Chloro-Phenyl)-Pyrimidine-4-Carboxylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.