Description

1H-Indene-1,3(2H)-Dione, 2-(3,4-Dihydro-6,7,8-Trimethoxy-4-Oxo-3-Phenyl-2-Quinazolinyl)- is a high-purity, complex heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its unique molecular architecture, featuring fused indenedione and quinazolinone moieties, makes it a valuable scaffold for synthesizing novel bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential kinase inhibitors, anticancer agents, and other therapeutic compounds targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and combinatorial chemistry libraries for drug discovery programs.
• Agrochemical Development: Intermediate in the research and synthesis of novel herbicides, fungicides, or plant growth regulators with specific modes of action.
• Fine Chemical Synthesis: Serves as a specialized precursor for creating complex dyes, pigments, or functional materials requiring specific heterocyclic structures.
• Biochemical Tool Compound: Potential use in developing probes or assay components for studying enzymatic activity or cellular signaling processes in life sciences.

Basic Information

Product Name	1H-Indene-1,3(2H)-Dione, 2-(3,4-Dihydro-6,7,8-Trimethoxy-4-Oxo-3-Phenyl-2-Quinazolinyl)-
CAS No.	858645-51-9
Molecular Formula	C26H20N2O6
Molecular Weight	456.45 g/mol
Synonyms	2-(3,4-Dihydro-6,7,8-trimethoxy-4-oxo-3-phenylquinazolin-2-yl)-1H-indene-1,3(2H)-dione; 3-Phenyl-6,7,8-trimethoxy-2-(1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-3,4-dihydroquinazolin-4(2H)-one; 2-(3,4-Dihydro-6,7,8-trimethoxy-4-oxo-3-phenyl-2-quinazolinyl)-1H-indene-1,3(2H)-dione; (2-(3,4-Dihydro-6,7,8-trimethoxy-4-oxo-3-phenylquinazolin-2-yl)-1H-indene-1,3(2H)-dione); CAS 858645-51-9
EINECS	Contact for details

Quality Control

Our production of 1H-Indene-1,3(2H)-Dione, 2-(3,4-Dihydro-6,7,8-Trimethoxy-4-Oxo-3-Phenyl-2-Quinazolinyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.