Description

4-Amino-2-Chloro-Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-purity, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive amino and chloro substituents, which enable precise molecular modifications and the construction of complex heterocyclic systems. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other biologically active pyrimidine-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the pyrimidine scaffold.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, including coupling reactions, substitutions, and cyclizations to create diverse chemical libraries.
• Material Science: Investigated as a monomer or building block for specialty polymers and advanced organic materials with specific electronic properties.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-Amino-2-Chloro-Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	858269-13-3
Molecular Formula	C7H7ClN3O2
Molecular Weight	200.60 g/mol
Synonyms	Methyl 4-Amino-2-chloropyrimidine-5-carboxylate; 2-Chloro-4-aminopyrimidine-5-carboxylic acid methyl ester; 5-Carbomethoxy-2-chloro-4-aminopyrimidine; 4-Amino-2-chloro-5-pyrimidinecarboxylic acid methyl ester; 858269-13-3; Methyl 2-chloro-4-aminopyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Chloro-Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.