Description

3-(2-Aminoethyl)-3,4-Dihydroquinazolin-4-One Dihydrochloride is a high-purity, dihydrochloride salt derivative of a quinazolinone-based organic compound. This specialized intermediate is of significant value in pharmaceutical research and development, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Tool Compound: May be utilized in vitro to study enzyme inhibition or receptor binding activities for target validation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A foundational substrate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-(2-Aminoethyl)-3,4-Dihydroquinazolin-4-One Dihydrochloride
CAS No.	858236-77-8
Molecular Formula	C₁₀H₁₄Cl₂N₄O
Molecular Weight	277.15 g/mol
Synonyms	3-(2-Aminoethyl)-3,4-dihydro-4-quinazolinone dihydrochloride; 4(3H)-Quinazolinone, 3-(2-aminoethyl)-3,4-dihydro-, dihydrochloride; 3-(2-Aminoethyl)-3,4-dihydroquinazolin-4-one hydrochloride (1:2); 858236-77-8; Quinazolinone dihydrochloride derivative; 2-(4-Oxo-3,4-dihydroquinazolin-3-yl)ethan-1-aminium chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(2-Aminoethyl)-3,4-Dihydroquinazolin-4-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.