Description

2-(4-Chlorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone is a high-purity, synthetically valuable pyrimidinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a chlorophenyl and nitro-substituted pyrimidinone core, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used as a building block for developing next-generation herbicides, fungicides, and insecticides.
• Chemical Synthesis: Serves as a versatile scaffold in heterocyclic and medicinal chemistry for creating diverse compound libraries.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and reaction mechanisms.
• Material Science: Potential intermediate for synthesizing specialty chemicals and functional materials.

Basic Information

Product Name	2-(4-Chlorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone
CAS No.	857427-78-2
Molecular Formula	C10H6ClN3O4
Molecular Weight	267.63 g/mol
Synonyms	5-Nitro-6-hydroxy-2-(4-chlorophenyl)-4(3H)-pyrimidinone; 2-(4-Chlorophenyl)-5-nitro-6-hydroxy-4-pyrimidinone; 4(3H)-Pyrimidinone, 2-(4-chlorophenyl)-6-hydroxy-5-nitro-; 857427-78-2; 6-Hydroxy-2-(4-chlorophenyl)-5-nitro-4(3H)-pyrimidinone; 5-Nitro-2-(p-chlorophenyl)-6-hydroxy-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-6-Hydroxy-5-Nitro-4(3H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its complex heterocyclic structure, prolonged exposure to high humidity or extreme temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.