Description

5-[(4-Aminophenyl)Ethynyl]Pyrimidin-2-Amine is a high-purity, functionalized pyrimidine derivative featuring a conjugated ethynyl linker and primary amine groups, making it a versatile and valuable synthetic intermediate. This compound is specifically engineered for advanced research and development in pharmaceutical chemistry and materials science, where precise molecular architecture is critical. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products, leveraging its heterocyclic core.
• Organic Electronic Materials: Acts as a precursor for conjugated polymers or small molecules used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors) due to its rigid, π-conjugated structure.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, where the amine groups allow for further functionalization.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory synthesis in both university and corporate research laboratories.

Basic Information

Product Name	5-[(4-Aminophenyl)Ethynyl]Pyrimidin-2-Amine
CAS No.	857265-90-8
Molecular Formula	C12H10N4
Molecular Weight	210.24 g/mol
Synonyms	2-Amino-5-[(4-aminophenyl)ethynyl]pyrimidine; 5-[(4-Aminophenyl)ethynyl]-2-pyrimidinamine; 5-(4-Aminophenylethynyl)pyrimidin-2-amine; 2-Pyrimidinamine, 5-[(4-aminophenyl)ethynyl]-; 857265-90-8; 5-(4-Aminophenylethynyl)-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 5-[(4-Aminophenyl)Ethynyl]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.