Description

Potassium 5H-Pyrrolo[3,2-D]Pyrimidine-6-Carboxylate is a high-purity, organometallic salt derivative of a fused pyrrolopyrimidine heterocycle, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive carboxylate salt form, which facilitates solubility and downstream functionalization under mild conditions, essential for constructing complex molecular architectures. This compound is particularly vital for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require precise intermediates for the development of novel active ingredients, such as kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted drug candidates, particularly in oncology and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides that require specific heterocyclic cores for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Investigated for the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its conjugated structure and metal-binding capability.

Basic Information

Product Name	Potassium 5H-Pyrrolo[3,2-D]Pyrimidine-6-Carboxylate
CAS No.	857204-03-6
Molecular Formula	C7H4KN3O2
Molecular Weight	201.23 g/mol
Synonyms	Potassium 5H-pyrrolo[3,2-d]pyrimidine-6-carboxylate; 5H-Pyrrolo[3,2-d]pyrimidine-6-carboxylic acid, potassium salt; 6-Carboxy-5H-pyrrolo[3,2-d]pyrimidine potassium salt; Potassium 6-carboxy-5H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine-6-carboxylic acid potassium derivative
EINECS	Contact for details

Quality Control

Our Potassium 5H-Pyrrolo[3,2-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the stringent requirements for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.