Description

[2-(5-Chloro-Pyrimidin-2-Yloxy)-Ethyl]-Dimethyl-Amine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active molecules, offering a versatile chemical handle for further functionalization. It is primarily needed by pharmaceutical research and agrochemical development teams seeking to create new libraries of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Ligand and Catalyst Development: The pyrimidine core and amine functionality make it a candidate for developing novel ligands in coordination chemistry and catalysis.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials requiring specific heterocyclic architectures.

Basic Information

Product Name	[2-(5-Chloro-Pyrimidin-2-Yloxy)-Ethyl]-Dimethyl-Amine
CAS No.	857011-22-4
Molecular Formula	C8H12ClN3O
Molecular Weight	201.65 g/mol
Synonyms	2-[(5-Chloro-2-pyrimidinyl)oxy]-N,N-dimethylethanamine; N,N-Dimethyl-2-((5-chloropyrimidin-2-yl)oxy)ethanamine; 5-Chloro-2-(2-(dimethylamino)ethoxy)pyrimidine; 2-(2-Dimethylaminoethoxy)-5-chloropyrimidine; Ethanamine, 2-[(5-chloro-2-pyrimidinyl)oxy]-N,N-dimethyl-; (2-((5-Chloropyrimidin-2-yl)oxy)ethyl)dimethylamine
EINECS	Contact for details

Quality Control

Our [2-(5-Chloro-Pyrimidin-2-Yloxy)-Ethyl]-Dimethyl-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.