Description

4-Bromo-5-(Bromomethyl)-6-Chloro-2-Methylpyrimidine is a high-purity, multi-halogenated pyrimidine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl and halogen substituents, makes it a versatile and critical intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the pyrimidine core is a common bioactive scaffold.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to introduce functionalized pyrimidine units into more complex molecules.
• Material Science: Investigated for the creation of organic electronic materials, ligands for metal-organic frameworks (MOFs), and other specialty polymers.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Bromo-5-(Bromomethyl)-6-Chloro-2-Methylpyrimidine
CAS No.	856975-67-2
Molecular Formula	C6H5Br2ClN2
Molecular Weight	308.38 g/mol
Synonyms	5-(Bromomethyl)-4-bromo-6-chloro-2-methylpyrimidine; 2-Methyl-4-bromo-5-bromomethyl-6-chloropyrimidine; 4-Bromo-5-bromomethyl-6-chloro-2-methylpyrimidine; 6-Chloro-4-bromo-5-(bromomethyl)-2-methylpyrimidine; Pyrimidine, 4-bromo-5-(bromomethyl)-6-chloro-2-methyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-5-(Bromomethyl)-6-Chloro-2-Methylpyrimidine is manufactured and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Our quality assurance system is designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.