Description

3-(5-Aminopyrimidin-4-Yl)Benzoic Acid is a high-purity, heterocyclic benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a reactive carboxylic acid group and an aminopyrimidine moiety, enabling its use in the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Scaffold: Used as a core scaffold or a functionalized fragment in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Agrochemical Research: Employed in the synthesis of advanced active ingredients for crop protection products.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science: Potential monomer or functional additive in the development of specialty polymers with specific electronic or binding properties.

Basic Information

Product Name	3-(5-Aminopyrimidin-4-Yl)Benzoic Acid
CAS No.	856905-14-1
Molecular Formula	C11H9N3O2
Molecular Weight	215.21 g/mol
Synonyms	4-(3-Carboxyphenyl)-5-pyrimidinamine; 5-Amino-4-(3-carboxyphenyl)pyrimidine; 3-(5-Amino-4-pyrimidinyl)benzoic acid; Benzoic acid, 3-(5-amino-4-pyrimidinyl)-; 856905-14-1
EINECS	Contact for details

Quality Control

Our 3-(5-Aminopyrimidin-4-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.