Description

2-[(Diethylamino)Methyl]-5,6-Dimethylthieno[2,3-D]Pyrimidine-4-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique thienopyrimidine scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing process of complex active drug substances.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-[(Diethylamino)Methyl]-5,6-Dimethylthieno[2,3-D]Pyrimidine-4-Thiol
CAS No.	855991-74-1
Molecular Formula	C15H21N3S2
Molecular Weight	307.48 g/mol
Synonyms	5,6-Dimethyl-2-[(diethylamino)methyl]thieno[2,3-d]pyrimidine-4-thiol; 2-[(Diethylamino)methyl]-5,6-dimethyl-4-thioxo-3,4-dihydrothieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine-4-thiol, 2-[(diethylamino)methyl]-5,6-dimethyl-; CAS 855991-74-1
EINECS	Contact for details

Quality Control

Our 2-[(Diethylamino)Methyl]-5,6-Dimethylthieno[2,3-D]Pyrimidine-4-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.