Description

1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of novel antibacterial agents, particularly within the fluoroquinolone class. It is essential for pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of next-generation antibiotics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new antibacterial drug candidates.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Academic & Contract Research: Utilized in medicinal chemistry research to study structure-activity relationships and develop new therapeutic agents.
• Process Chemistry: Employed in scaling up synthetic routes for commercial API production under GMP conditions.

Basic Information

Product Name	1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	855661-71-1
Molecular Formula	C21H24FN3O4
Molecular Weight	401.44 g/mol
Synonyms	7-[(4aR,7aS)-Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; WCK 771; WCK-771; WCK 771 Intermediate; (4aR,7aS)-7-(1-Cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-3-yl)octahydro-1H-pyrrolo[3,4-b]pyridine-6-carboxylic acid; Levonadifloxacin Intermediate; Levonadifloxacin (WCK 771) Intermediate
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting specifications suitable for pharmaceutical R&D and GMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.