Description

4,5-Difluoro-1,2-Benzenedimethanol is a high-value fluorinated aromatic building block, specifically a difluorinated benzenedimethanol derivative. This compound is essential for introducing both fluorine atoms and hydroxymethyl functional handles into complex molecular architectures, enabling precise tuning of electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry, agrochemical development, and the synthesis of specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated components in electronic display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve thermal stability, chemical resistance, and surface properties.
• Cross-linking Agent: Utilized in epoxy and other resin systems where its dual hydroxyl functionality enables controlled polymerization.
• Organic Synthesis Reagent: A versatile precursor for further functionalization to create complex ligands, catalysts, and fine chemicals.

Basic Information

Product Name	4,5-Difluoro-1,2-Benzenedimethanol
CAS No.	854519-97-4
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	1,2-Bis(hydroxymethyl)-4,5-difluorobenzene; 4,5-Difluorobenzene-1,2-dimethanol; 4,5-Difluorophthalyl Alcohol; 4,5-Difluoro-1,2-bis(hydroxymethyl)benzene; 4,5-Difluorobenzene-1,2-diyldimethanol; 4,5-DFBDM; 4,5-Difluorophthalic Alcohol
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-1,2-Benzenedimethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.