Description

7-(Chloromethyl)-2-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One is a high-value, heterocyclic organic compound featuring a fused thiadiazolopyrimidinone core, serving as a critical synthetic intermediate in advanced chemical synthesis. Its unique molecular architecture, combining a reactive chloromethyl group with a complex nitrogen-sulfur heterocycle, makes it an essential building block for constructing novel pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, antiviral compounds, and enzyme inhibitors.
• Agrochemical Research: Building block for developing new generations of herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Used in the research and development of advanced organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	7-(Chloromethyl)-2-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One
CAS No.	854035-94-2
Molecular Formula	C8H6ClN3OS
Molecular Weight	227.67 g/mol
Synonyms	2-Methyl-7-(chloromethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one; 7-(Chloromethyl)-2-methyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one; [1,3,4]Thiadiazolo[3,2-a]pyrimidin-5-one, 7-(chloromethyl)-2-methyl-; Thiadiazolo[3,2-a]pyrimidin-5-one derivative; CAS 854035-94-2
EINECS	Contact for details

Quality Control

Our production of 7-(Chloromethyl)-2-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.