Description

4-Chloro-7-(4-Methoxybenzyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest due to its role as a key synthetic building block in the development of novel, small-molecule therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry, particularly for oncology and kinase-targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted kinase inhibitors and other bioactive molecules.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary compounds for clinical trials.

Basic Information

Product Name	4-Chloro-7-(4-Methoxybenzyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	853680-76-9
Molecular Formula	C14H14ClN3O
Molecular Weight	275.73 g/mol
Synonyms	4-Chloro-7-[(4-methoxyphenyl)methyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(4-methoxybenzyl)-5,6,7-trihydropyrrolo[2,3-d]pyrimidine; 853680-76-9; Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-[(4-methoxyphenyl)methyl]-6,7-dihydro-5H-; 4-Chloro-7-(p-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(4-Methoxybenzyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.