Description

4-(Piperazin-1-Yl)-1H-Pyrrolo[2,3-D]Pyrimidine Dihydrochloride is a high-purity, heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This dihydrochloride salt form offers enhanced stability and solubility, making it a critical synthetic intermediate for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted cancer therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for drug discovery.
• Biochemical Reagent: Serves as a reference standard or a substrate analog in enzymatic assays and biochemical studies.
• Organic Synthesis: Employed as a versatile precursor for constructing complex heterocyclic scaffolds with piperazine and pyrrolopyrimidine motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	4-(Piperazin-1-Yl)-1H-Pyrrolo[2,3-D]Pyrimidine Dihydrochloride
CAS No.	853680-06-5
Molecular Formula	C10H14Cl2N6
Molecular Weight	289.17 g/mol
Synonyms	4-(1-Piperazinyl)-1H-pyrrolo[2,3-d]pyrimidine dihydrochloride; 1H-Pyrrolo[2,3-d]pyrimidine, 4-(1-piperazinyl)-, dihydrochloride; 4-Piperazin-1-yl-1H-pyrrolo[2,3-d]pyrimidine dihydrochloride; 4-(Piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine dihydrochloride; Pyrrolo[2,3-d]pyrimidine, 4-(piperazinyl)-, dihydrochloride; 853680-06-5; 4-(1-Piperazinyl)-7H-pyrrolo[2,3-d]pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Piperazin-1-Yl)-1H-Pyrrolo[2,3-D]Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.