Description

4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylic Acid is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic precursor in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein functions.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, high-performance crop protection agents.
• Academic Research: Employed in universities and research institutes for methodological development in heterocyclic chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.

Basic Information

Product Name	4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylic Acid
CAS No.	853058-43-2
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-7-carboxy-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid; 853058-43-2; Pyrrolo[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro-5H-; 4-Chloro-7-pyrrolo[3,2-d]pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.