Description

Ethyl 4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate is a high-value heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound Development: Serves as a starting material for creating probes to study biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Employed in university and institutional labs for novel heterocyclic chemistry and methodology development.

Basic Information

Product Name	Ethyl 4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate
CAS No.	853058-42-1
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	4-Chloro-7-(ethoxycarbonyl)-5H-pyrrolo[3,2-d]pyrimidine; Ethyl 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate; 853058-42-1; 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester; 7-Carbethoxy-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro-5H-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidine-7-Carboxylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.