Description

Bzl-Nle-Ome CAS NO 853017-06-8 is a protected amino acid derivative, specifically N-Benzyloxycarbonyl-Norleucine Methyl Ester, widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptides with specific sequences and properties. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for drug discovery, development of therapeutic peptides, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected amino acid monomer for the sequential assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the production of custom peptides and peptide fragments.
• Pharmaceutical Intermediate: Acts as a crucial precursor in the research and development of novel peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Provides a reactive handle for attaching peptides to other molecules, surfaces, or probes in bioconjugation chemistry.
• Biochemical Research: Employed in academic and industrial laboratories to study protein structure-function relationships and enzyme-substrate interactions.
• Production of Peptide Libraries: Used in combinatorial chemistry to generate diverse arrays of peptides for high-throughput screening against biological targets.

Basic Information

Product Name	Bzl-Nle-Ome
CAS No.	853017-06-8
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	N-Cbz-Norleucine Methyl Ester; Z-Nle-OMe; Nα-Benzyloxycarbonyl-L-norleucine Methyl Ester; (S)-Methyl 2-((((benzyloxy)carbonyl)amino)hexanoate; Cbz-Norleucine-OMe; Benzyl N-(1-methoxy-1-oxohexan-2-yl)carbamate; N-Carbobenzoxy-L-norleucine Methyl Ester
EINECS	Contact for details

Quality Control

Our Bzl-Nle-Ome is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications like peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a corresponding Certificate of Analysis (COA). We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.