Description

4(1H)-Quinazolinone, 2,3-Dihydro-2-[3-Nitro-4-(1-Piperidinyl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Biochemical Tool Compound: Employed in vitro and in vivo to study and validate novel biological targets and signaling pathways.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value molecules in milligram to kilogram scales for preclinical development.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Product Name	4(1H)-Quinazolinone, 2,3-Dihydro-2-[3-Nitro-4-(1-Piperidinyl)Phenyl]-
CAS No.	852938-33-1
Molecular Formula	C19H18N4O3
Molecular Weight	350.37 g/mol
Synonyms	2,3-Dihydro-2-[3-nitro-4-(1-piperidinyl)phenyl]-4(1H)-quinazolinone; 2-[3-Nitro-4-(piperidin-1-yl)phenyl]-2,3-dihydro-4(1H)-quinazolinone; 852938-33-1; 4(1H)-Quinazolinone, 2,3-dihydro-2-[3-nitro-4-(1-piperidinyl)phenyl]-; 2-(3-Nitro-4-piperidin-1-yl-phenyl)-1,4-dihydro-2H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.