Description

Traf6 Peptide CAS NO 852805-92-6 is a synthetic peptide sequence designed to mimic a specific functional domain of the TNF Receptor-Associated Factor 6 protein, a key signaling adaptor in immune and inflammatory pathways. This high-purity biochemical tool is critical for researchers investigating intracellular signal transduction, particularly in the context of innate immunity, osteoclastogenesis, and lymphocyte activation. It serves as an essential reagent for pharmaceutical R&D, academic research in immunology and cell biology, and the development of targeted therapeutic strategies.

Application

• Biochemical Research: Used as a competitive inhibitor or binding partner in in vitro assays to study TRAF6-mediated signaling cascades, such as NF-κB and MAPK activation.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify novel small-molecule or biologic inhibitors that disrupt the TRAF6 interaction interface.
• Cell Signaling Studies: Essential for elucidating the role of TRAF6 in specific cellular contexts, including osteoclast differentiation, dendritic cell maturation, and Toll-like receptor (TLR) signaling.
• Antibody Development & Validation: Serves as a key antigen for generating and characterizing antibodies specific to the TRAF6 protein or its binding domains.
• Proteomics & Interaction Mapping: Utilized in pull-down assays, co-immunoprecipitation experiments, and surface plasmon resonance (SPR) to map protein-protein interaction networks.
• Therapeutic Peptide Development: Acts as a lead compound or template for designing peptide-based therapeutics aimed at modulating inflammatory and autoimmune diseases.

Basic Information

Item	Detail
Product Name	Traf6 Peptide
CAS No.	852805-92-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TRAF6-derived peptide; TNF Receptor-Associated Factor 6 peptide; TRAF6 signaling peptide; TRAF6 binding domain peptide; TRAF6 inhibitory peptide; CAS 852805-92-6
EINECS	Contact for details

Quality Control

Every batch of our Traf6 Peptide is manufactured and analyzed under stringent quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data, including mass spectrometry (MS) for sequence confirmation and high-performance liquid chromatography (HPLC) for purity assessment. A Certificate of Analysis (COA) detailing batch-specific results is available for all orders, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Solubility	Soluble in water or appropriate aqueous buffers
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.