Description

Pyrimidin-4-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing pyrimidine scaffolds.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides with targeted modes of action.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Ligand Synthesis: Utilized for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Pyrimidin-4-Ylboronic Acid
CAS No.	852362-24-4
Molecular Formula	C4H5BN2O2
Molecular Weight	123.91 g/mol
Synonyms	4-Pyrimidinylboronic Acid; (Pyrimidin-4-yl)boronic Acid; 4-Boronopyrimidine; Pyrimidine-4-boronic Acid; 4-Pyrimidineboronic Acid; B-(4-Pyrimidinyl)boronic Acid; 852362-24-4; Pyrimidin-4-ylboronic acid pinacol ester (protected form).
EINECS	Contact for details

Quality Control

Our Pyrimidin-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.