Description

4-Chloro-1-(3-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. This compound is valued for its role as a versatile synthetic building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing selective enzyme modulators in biochemical assays.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the custom synthesis of complex active pharmaceutical ingredients (APIs) and new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-1-(3-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	852314-01-3
Molecular Formula	C11H6Cl2N4
Molecular Weight	265.10 g/mol
Synonyms	4-Chloro-1-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-(3-chlorophenyl)-; 852314-01-3; 4-Chloro-1-(3-chlorophenyl)pyrazolo[3,4-d]pyrimidine; 3-Chlorophenyl-4-chloropyrazolopyrimidine; 4-Chloro-1-(m-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(3-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.