Description

1-(2,4-Dimethylphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ol is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for the synthesis of targeted therapeutic agents, particularly kinase inhibitors used in oncology research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

This specialized intermediate is designed for advanced synthetic applications, primarily within life sciences research and development.

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Oncology Research: Used in the discovery and development of potential anti-cancer drugs targeting specific enzymatic pathways.
• Biochemical Tool Compound: Serves as a precursor for creating probes and inhibitors used to study cellular signaling mechanisms.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and the production of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	1-(2,4-Dimethylphenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Ol
CAS No.	852313-95-2
Molecular Formula	C13H12N4O
Molecular Weight	240.26 g/mol
Synonyms	4-Hydroxy-1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol, 1-(2,4-dimethylphenyl)-; 852313-95-2; 1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol; Pyrazolopyrimidin-4-ol derivative; Kinase inhibitor intermediate; 1-(2,4-Xylyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. We offer material produced under ISO 9001 quality systems, with optional production in facilities operating under current Good Manufacturing Practice (cGMP) guidelines for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment, and comprehensive analytical data is available upon request to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.