Description

4-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D] Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 852219-10-4. This compound serves as a critical building block in the synthesis of targeted therapeutic agents, offering precise chemical functionality for complex molecular construction. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other biologically active small molecules.
• Oncology Drug Discovery: Used in research and development pipelines for creating novel anti-cancer therapeutics.
• Chemical Biology Research: Employed as a molecular probe or scaffold in structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Serves as a critical raw material for process optimization and commercial-scale Active Pharmaceutical Ingredient (API) manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development programs.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	4-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D] Pyrimidine-5-Carboxylic Acid
CAS No.	852219-10-4
Molecular Formula	C₁₄H₁₄ClN₃O₂
Molecular Weight	291.73 g/mol
Synonyms	4-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 852219-10-4; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 4-chloro-7-cyclopentyl-; 4-Chloro-7-cyclopentyl-5-carboxy-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-cyclopentyl-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-D] Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.