Description

4-Amino-6-chloro-5-fluoropyrimidine is a high-purity fluorinated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its multifunctional reactivity, serving as a versatile scaffold for constructing complex molecules with tailored properties. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated nucleoside analogs and other active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and stability.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential use in the development of specialty chemicals, dyes, and advanced organic materials requiring specific heterocyclic architectures.

Basic Information

Product Name	4-Amino-6-chloro-5-fluoropyrimidine
CAS No.	851984-15-1
Molecular Formula	C4H4ClFN4
Molecular Weight	162.55 g/mol
Synonyms	5-Fluoro-6-chloropyrimidin-4-amine; 6-Chloro-5-fluoropyrimidin-4-amine; 4-Amino-5-fluoro-6-chloropyrimidine; 4-Pyrimidinamine, 6-chloro-5-fluoro-; 5-Fluoro-4-amino-6-chloropyrimidine; 6-Chloro-5-fluoro-4-pyrimidinamine; ACFP; 851984-15-1
EINECS	Contact for details

Quality Control

Our 4-Amino-6-chloro-5-fluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.