Description

2-(4-Boc-Piperazino-1-Yl)-6-Fluorobenzaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a reactive aldehyde group. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile reactive sites.
• Protease & Kinase Inhibitor Synthesis: Serves as a precursor in the development of targeted enzyme inhibitors.
• Chemical Biology: Employed in the design and synthesis of molecular probes for biological target identification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Used in university laboratories for investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Boc-Piperazino-1-Yl)-6-Fluorobenzaldehyde
CAS No.	851753-43-0
Molecular Formula	C₁₆H₂₁FN₂O₃
Molecular Weight	308.35 g/mol
Synonyms	6-Fluoro-2-[4-(tert-butoxycarbonyl)piperazin-1-yl]benzaldehyde; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-6-fluorobenzaldehyde; 2-(N-Boc-piperazinyl)-6-fluorobenzaldehyde; 2-(4-Boc-piperazin-1-yl)-6-fluorobenzaldehyde; tert-Butyl 4-(2-formyl-3-fluorophenyl)piperazine-1-carboxylate; 851753-43-0; Boc-protected fluoro benzaldehyde piperazine derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazino-1-Yl)-6-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.