Description

2(3H)-Thiazolone, 3,4-Dimethyl-5-[2-[[4-(1-Piperazinyl)Phenyl]Amino]-4-Pyrimidinyl]- is a sophisticated heterocyclic organic compound featuring a fused thiazolone and pyrimidine core, functionalized with a piperazine-substituted aniline moiety. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate or research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D organizations and fine chemical synthesis specialists engaged in creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Core scaffold for the development of novel kinase inhibitors due to its pyrimidine and piperazine motifs.
• Chemical Biology Probes: Used in academic and industrial research to study enzyme function and cellular signaling processes.
• Medicinal Chemistry Optimization: Serves as a starting point for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• High-Throughput Screening Libraries: Included in compound libraries for screening against novel biological targets.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	2(3H)-Thiazolone, 3,4-Dimethyl-5-[2-[[4-(1-Piperazinyl)Phenyl]Amino]-4-Pyrimidinyl]-
CAS No.	851439-14-0
Molecular Formula	C19H22N6OS
Molecular Weight	382.48 g/mol
Synonyms	3,4-Dimethyl-5-[2-[[4-(1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-2(3H)-thiazolone; 3,4-Dimethyl-5-(2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)thiazol-2(3H)-one; 851439-14-0; Thiazolone derivative with piperazinylphenylaminopyrimidine; 5-[2-({4-[1-Piperazinyl]phenyl}amino)-4-pyrimidinyl]-3,4-dimethyl-2(3H)-thiazolone
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.