Description

5-Pyrimidinecarbonitrile, 4-Amino-2-(2,5-Dihydroxyphenyl)-6-(3-Piperidinyl)-, (Hcl Salt) is a high-purity, complex heterocyclic compound designed for advanced research and development. This molecule is valued for its unique structural features, including a pyrimidine core, a piperidine moiety, and a dihydroxyphenyl group, which make it a versatile building block in synthetic chemistry. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and as a key intermediate in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target identification.
• Organic Synthesis: Acts as a sophisticated intermediate for constructing complex polycyclic or heterocyclic frameworks in academic and industrial laboratories.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-Amino-2-(2,5-Dihydroxyphenyl)-6-(3-Piperidinyl)-, (Hcl Salt)
CAS No.	851382-44-0
Molecular Formula	C16H17N5O2 • HCl
Molecular Weight	355.80 g/mol
Synonyms	4-Amino-2-(2,5-dihydroxyphenyl)-6-(piperidin-3-yl)pyrimidine-5-carbonitrile hydrochloride; 4-Amino-2-(2,5-dihydroxyphenyl)-6-(3-piperidinyl)-5-pyrimidinecarbonitrile monohydrochloride; 851382-44-0; UNII-6K8T8VK8Q4; 6K8T8VK8Q4; CHEMBL3185147; AKOS025147064; 4-Amino-2-(2,5-dihydroxyphenyl)-6-(3-piperidyl)pyrimidine-5-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 5-Pyrimidinecarbonitrile, 4-Amino-2-(2,5-Dihydroxyphenyl)-6-(3-Piperidinyl)-, (Hcl Salt) CAS 851382-44-0 is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.