Description

Pyrimidin-2-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds containing pyrimidine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Building block for creating organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Biology & Medicinal Chemistry: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and candidate drug molecules.
• Cross-Coupling Reactions: Specifically designed as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions to introduce the pyrimidin-2-yl moiety.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	Pyrimidin-2-Ylboronic Acid
CAS No.	851199-85-4
Molecular Formula	C4H5BN2O2
Molecular Weight	123.91 g/mol
Synonyms	2-Pyrimidineboronic Acid; (Pyrimidin-2-yl)boronic Acid; 2-Boronopyrimidine; Pyrimidin-2-ylboronic acid; Pyrimidine-2-boronic Acid; 2-Pyrimidylboronic Acid; B-(2-Pyrimidinyl)boronic Acid; 851199-85-4
EINECS	Contact for details

Quality Control

Every batch of Pyrimidin-2-Ylboronic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation, ensuring the material meets the stringent requirements of pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.