Description

2-[2-(4-Bromophenyl)Vinyl]-4-Chloro-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in oncology and central nervous system (CNS) disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors, relevant in oncology research.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and cellular signaling.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.

Basic Information

Product Name	2-[2-(4-Bromophenyl)Vinyl]-4-Chloro-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidine
CAS No.	851169-47-6
Molecular Formula	C20H16BrClN2S
Molecular Weight	431.78 g/mol
Synonyms	4-Chloro-2-[(E)-2-(4-bromophenyl)ethenyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine; 2-[(E)-2-(4-Bromophenyl)vinyl]-4-chloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine; 4-Chloro-2-[2-(4-bromophenyl)vinyl]-5,6,7,8-tetrahydrothieno[2',3':4,5]thieno[2,3-d]pyrimidine; Benzothienopyrimidine derivative, CAS 851169-47-6; Advanced Heterocyclic Building Block 851169-47-6
EINECS	Contact for details

Quality Control

Our production of 2-[2-(4-Bromophenyl)Vinyl]-4-Chloro-5,6,7,8-Tetrahydro[1]Benzothieno[2,3-D]Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be handled in a well-ventilated area, and prolonged exposure to high humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.