Description

3-(2,5,7-Trimethyl-Pyrazolo[1,5-A]Pyrimidin-6-Yl)-Propionic Acid is a high-purity, functionalized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyrazolopyrimidine scaffold, which serves as a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel drug candidates and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of new active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that leverage the pyrazolopyrimidine core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED device fabrication due to its rigid, conjugated structure.
• Ligand Synthesis for Catalysis: Functionalized to create novel nitrogen-donor ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Biochemical Research: Employed as a probe or scaffold in biochemical assays to study enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for advanced polymers and coatings to impart specific thermal or electronic properties.

Basic Information

Product Name	3-(2,5,7-Trimethyl-Pyrazolo[1,5-A]Pyrimidin-6-Yl)-Propionic Acid
CAS No.	851116-09-1
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	3-(2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-yl)propanoic acid; 6-(2-Carboxyethyl)-2,5,7-trimethylpyrazolo[1,5-a]pyrimidine; 2,5,7-Trimethyl-6-(2-carboxyethyl)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine-6-propanoic acid, 2,5,7-trimethyl-; TPPA; 851116-09-1; 3-(2,5,7-Trimethylpyrazolo[1,5-a]pyrimidin-6-yl)propionic acid
EINECS	Contact for details

Quality Control

Our 3-(2,5,7-Trimethyl-Pyrazolo[1,5-A]Pyrimidin-6-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.