Description

5-Methyl-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for constructing potent and selective kinase inhibitors, targeting specific enzymatic pathways involved in disease progression.
• Chemical Biology Research: Used as a probe or tool compound in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for new Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional laboratories for medicinal chemistry programs and the discovery of new bioactive molecules.

Basic Information

Product Name	5-Methyl-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	850628-76-1
Molecular Formula	C9H9N3OS
Molecular Weight	207.25 g/mol
Synonyms	5-Methyl-2-(methylthio)-8H-pyrido[2,3-d]pyrimidin-7-one; 5-Methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one; 850628-76-1; Pyrido[2,3-d]pyrimidin-7(8H)-one, 5-methyl-2-(methylthio)-; 2-Methylmercapto-5-methyl-pyrido[2,3-d]pyrimidin-7-one; 5-Methyl-2-(methylthio)-7,8-dihydropyrido[2,3-d]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full analytical data are available upon request, and custom purity grades can be discussed to support your specific project phase from discovery to development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades Available)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.