Description

(2-Amino-4,6-Dichloropyrimidin-5-Yl)Methanol is a high-purity pyrimidine derivative building block essential for advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other heterocyclic APIs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in polymer chemistry.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic chemistry.

Basic Information

Product Name	(2-Amino-4,6-Dichloropyrimidin-5-Yl)Methanol
CAS No.	850554-81-3
Molecular Formula	C5H5Cl2N3O
Molecular Weight	194.02 g/mol
Synonyms	5-(Hydroxymethyl)-4,6-dichloropyrimidin-2-amine; 4,6-Dichloro-2-amino-5-pyrimidinemethanol; 2-Amino-4,6-dichloro-5-pyrimidinemethanol; (2-Amino-4,6-dichloro-5-pyrimidinyl)methanol; 4,6-Dichloro-2-aminopyrimidine-5-methanol; 5-Pyrimidinemethanol, 2-amino-4,6-dichloro-; 850554-81-3
EINECS	Contact for details

Quality Control

Our (2-Amino-4,6-Dichloropyrimidin-5-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.