Description

5-Methyl-3-Phenylpyrazolo[1,5-A]Pyrimidine-7-Thiol is a specialized heterocyclic compound belonging to the pyrazolopyrimidine class, serving as a critical building block in advanced organic synthesis. Its unique fused-ring structure with a thiol functional group makes it a valuable intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a ligand or building block for creating functional organic materials and metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential reagent for method development and exploratory synthetic chemistry in academic and CRO laboratories.
• Chemical Biology: Useful as a probe or scaffold in studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	5-Methyl-3-Phenylpyrazolo[1,5-A]Pyrimidine-7-Thiol
CAS No.	850238-91-4
Molecular Formula	C₁₃H₁₁N₃S
Molecular Weight	241.31 g/mol
Synonyms	5-Methyl-3-phenyl-7H-pyrazolo[1,5-a]pyrimidine-7-thione; 5-Methyl-3-phenylpyrazolo[1,5-a]pyrimidine-7-thiol; 7H-Pyrazolo[1,5-a]pyrimidine-7-thione, 5-methyl-3-phenyl-; 3-Phenyl-5-methylpyrazolo[1,5-a]pyrimidine-7-thiol; 5-Methyl-3-phenyl-7-thioxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-3-Phenylpyrazolo[1,5-A]Pyrimidine-7-Thiol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.